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TRAIL Induced Apoptosis is Enhanced by Inhibition of the MAPK and PI3K/AKT Pathways in Thyroid Cancer Cells

✍ Scribed by Gunda, V.; Bucur, O.; Varnau, J.; Lawler, J.; Khosravi-Far, R.; Parangi, S.

Book ID
122929207
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
104 KB
Volume
179
Category
Article
ISSN
0022-4804

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## Abstract We observed that treatment of prostate cancer cells for 24 h with magnolol, a phenolic component extracted from the root and stem bark of the oriental herb __Magnolia officinalis__, induced apoptotic cell death in a dose‐ and time‐dependent manner. A sustained inhibition of the major su