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Thioridazine induces apoptosis by targeting the PI3K/Akt/mTOR pathway in cervical and endometrial cancer cells

✍ Scribed by Kang, Sokbom; Dong, Seung Myung; Kim, Boh-Ram; Park, Mi Sun; Trink, Barry; Byun, Hyun-Jung; Rho, Seung Bae

Book ID
118795237
Publisher
Springer
Year
2012
Tongue
English
Weight
534 KB
Volume
17
Category
Article
ISSN
1360-8185

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✍ Dae-Hee Lee; Miroslaw-Jerzy Szczepanski; Yong J. Lee πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 413 KB

## Abstract We observed that treatment of prostate cancer cells for 24 h with magnolol, a phenolic component extracted from the root and stem bark of the oriental herb __Magnolia officinalis__, induced apoptotic cell death in a dose‐ and time‐dependent manner. A sustained inhibition of the major su