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TPA-Activated Transcription of the Human MnSOD Gene: Role of Transcription Factors SP-1 and Egr-1

✍ Scribed by Porntadavity, Sureerut; Xu, Yong; Kiningham, Kelley; Rangnekar, Vivek M.; Prachayasitikul, Virapong; St. Clair, Daret K.

Book ID
120587270
Publisher
Mary Ann Liebert
Year
2001
Tongue
English
Weight
307 KB
Volume
20
Category
Article
ISSN
1044-5498

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Specificity of transcriptional regulatio
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✍ Alia Al-Sarraj; Regina M. Day; Gerald Thiel πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 246 KB

## Abstract The transcription factors Sp1, Sp3, and Egr‐1 bind with their zinc finger DNA‐binding domains to GC‐rich sequences in the regulatory regions of their target genes. The similarity of the DNA‐binding sites of Sp1, Sp3, and Egr‐1 has triggered the hypothesis that they compete for the same