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TP53 mutation in ovarian carcinoma

✍ Scribed by M Murphy; D.T McManus; P.G Toner; S.E.H Russell

Book ID
117663851
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
278 KB
Volume
33
Category
Article
ISSN
0959-8049

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## Abstract The importance of somatic __TP53__ mutations and germline __TP53__ codon 72 genotype in the survival of women with epithelial ovarian cancer is controversial. Recent data suggest that a promoter polymorphism in the __MDM2__ gene may influence age of cancer onset in a gender‐specific fas