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Mutation and expression of the TP53 gene in early stage epithelial ovarian carcinoma

✍ Scribed by Mario M Leitao; Robert A Soslow; Rebecca N Baergen; Narciso Olvera; Crispinita Arroyo; Jeff Boyd

Book ID: 113959207
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 181 KB
Volume: 93
Category: Article
ISSN: 0090-8258
DOI: 10.1016/j.ygyno.2004.01.043

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## Abstract The importance of somatic __TP53__ mutations and germline __TP53__ codon 72 genotype in the survival of women with epithelial ovarian cancer is controversial. Recent data suggest that a promoter polymorphism in the __MDM2__ gene may influence age of cancer onset in a gender‐specific fas