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The relationship between vascularity, p53 gene mutations and distant metastatic disease in epithelial ovarian carcinoma

✍ Scribed by J.R. Girardi; M. Samuelson; A. Button; K. De Geest; D. Bender; A. Ahmed; M.J. Goodheart

Book ID
113963380
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
46 KB
Volume
123
Category
Article
ISSN
0090-8258

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## Abstract E‐cadherin mutations are found in 50% of diffuse‐type gastric carcinoma, but not in intestinal gastric carcinoma. Because cell–cell adhesion mediated by E‐cadherin plays an important role in epithelial cell survival, E‐cadherin mutations could alter the apoptotic behavior of tumor cells