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T.P.43 Enzyme replacement therapy in late-onset Pompe disease – A systematic literature review

✍ Scribed by Toscano, A.; Schoser, B.


Book ID
119333788
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
47 KB
Volume
22
Category
Article
ISSN
0960-8966

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Enzyme replacement therapy induces T-cel
✍ Miklos Banati; Zsolt Hosszu; Anita Trauninger; Laszlo Szereday; Zsolt Illes 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 330 KB

## Abstract ## Introduction: Enzyme replacement therapy (ERT) in ultra‐orphan Pompe disease generates anti‐rhGAA antibodies, which may interfere with efficacy. ## Methods: rhGAA‐specific T‐cell responses were examined at different time‐points in 6 Hungarian patients treated with rhGAA and compar