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Toxoplasma gondii: Inhibitory activity and encystation effect of securinine and pyrrolidine derivatives on Toxoplasma growth

✍ Scribed by Michael Holmes; Anna K. Crater; Bhartesh Dhudshia; Avinash N. Thadani; Sirinart Ananvoranich

Book ID: 113618095
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 433 KB
Volume: 127
Category: Article
ISSN: 0014-4894
DOI: 10.1016/j.exppara.2010.09.002

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## Abstract Most gastrointestinal stromal tumors (GISTs) have gain‐of‐function mutations of the c‐__kit__ gene. Previously, we found 2 types of gain‐of‐function mutation of the __PDGFRA__ gene, Val^561^ to Asp and Asp^842^ to Val, in about half of GISTs without c‐__kit__ gene mutations. Although th