Toxin-Induced K+ Efflux through the Na+ Channel of Neuroblastoma Cells
β Scribed by Yannick JACQUES; Georges ROMEY; Michel LAZDUNSKI
- Book ID
- 115119539
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 852 KB
- Volume
- 111
- Category
- Article
- ISSN
- 1432-1327
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The Na / pump (Na / , K / -ATPase) has been implicated in the regulation of many cellular functions, including cell volume regulation. The effects of inhibiting Na / pump activity on cell volume and taurine efflux were evaluated in the human neuroblastoma cell line CHP-100. Cell volume changes monit
The effects of fatty acids on voltage-dependent potassium (K Β§ channels in neuroblastoma cells were studied using the whole-cell current recording technique. At a concentration of 5 ~tM, unsaturated and medium chain length (C10-C14) saturated fatty acids accelerated the apparent inactivation of the