𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Toxicological studies on Globularia alypum and Zygophyllum gaetulum in rats

✍ Scribed by F. Skim; B. H. Lazrek; H. El Amri; A. Kaaya; M. Jana

Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
39 KB
Volume
12
Category
Article
ISSN
0951-418X

No coin nor oath required. For personal study only.

✦ Synopsis

This work examines the toxicological effects of Globularia alypum leaves and Zygophyllum gaetulum aerial parts used in the traditional treatment of diabetes mellitus in Morocco.

The LD 50 after oral administration of the plant infusions was higher than 10 g/kg body weight. Chronic toxicity was evaluated by analysis of biochemical and haematological parameters and by anatomohistopathological studies. It is suggested that these plants have no toxicological effects in rats.

📜 SIMILAR VOLUMES

Toxicological studies on the leaves of A
Toxicological studies on the leaves of Avicennia marina (mangrove) in rats
✍ B. H. Ali; A. K. Bashir 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 41 KB 👁 2 views

Haematological, biochemical and pathological effects in rats produced by the salt-tolerant plant Avicennia marina given at oral doses of 1 or 4 g kg ؊1 for three consecutive days or 0.5 g kg ؊1 day ؊1 for 28 consecutive days are reported. No overt behavioral changes, moribundity or mortality were se

New designer drug α-pyrrolidinovalerophe
New designer drug α-pyrrolidinovalerophenone (PVP): studies on its metabolism and toxicological detection in rat urine using gas chromatographic/mass spectrometric techniques
✍ Christoph Sauer; Frank T. Peters; Claudia Haas; Markus R. Meyer; Giselher Fritsc 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 227 KB

## Abstract The aim of the present study was to identify the metabolites of the new designer drug α‐pyrrolidinovalerophenone (PVP) in rat urine using GC/MS techniques. Eleven metabolites of PVP could be identified suggesting the following metabolic steps: hydroxylation of the side chain followed by

New designer drug 1-(3,4-methylenedioxyb
New designer drug 1-(3,4-methylenedioxybenzyl) piperazine (MDBP): studies on its metabolism and toxicological detection in rat urine using gas chromatography/mass spectrometry
✍ Roland F. Staack; Hans H. Maurer 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 147 KB

## Abstract Studies are described on the metabolism and toxicological analysis of the piperazine‐derived designer drug 1‐(3,4‐methylenedioxybenzyl)piperazine (MDBP) in rat urine using gas chromatography/mass spectrometry (GC/MS). The identified metabolites indicated that MDBP was metabolized by dem

Designer drug 2,4,5-trimethoxyamphetamin
Designer drug 2,4,5-trimethoxyamphetamine (TMA-2): Studies on its metabolism and toxicological detection in rat urine using gas chromatographic/mass spectrometric techniques
✍ Andreas H. Ewald; Giselher Fritschi; Hans H. Maurer 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 249 KB

## Abstract Studies are described on the metabolism and the toxicological detection of the amphetamine‐derived designer drug 2,4,5‐trimethoxyamphetamine (TMA‐2) in rat urine using gas chromatographic/mass spectrometric (GC/MS) techniques. The identified metabolites indicated that TMA‐2 was metaboli

New designer drug N-(1-phenylcyclohexyl)
New designer drug N-(1-phenylcyclohexyl)-3-ethoxypropanamine (PCEPA): Studies on its metabolism and toxicological detection in rat urine using gas chromatographic/mass spectrometric techniques
✍ Christoph Sauer; Frank T. Peters; Roland F. Staack; Giselher Fritschi; Hans H. M 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 488 KB

## Abstract Studies are described on the metabolism and toxicological detection of the phencyclidine‐derived designer drug __N__‐(1‐phenylcyclohexyl)‐3‐ethoxypropanamine (PCEPA) in rat urine using gas chromatographic/mass spectrometric techniques. The identified metabolites indicated that PCEPA was

New designer drug 1-(3-trifluoromethylph
New designer drug 1-(3-trifluoromethylphenyl) piperazine (TFMPP): gas chromatography/mass spectrometry and liquid chromatography/mass spectrometry studies on its phase I and II metabolism and on its toxicological detection in rat urine
✍ Roland F. Staack; Gieselher Fritschi; Hans H. Maurer 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 269 KB

## Abstract Studies are described on the phase I and II metabolism and the toxicological analysis of the piperazine‐derived designer drug 1‐(3‐trifluoromethylphenyl)piperazine (TFMPP) in rat urine using gas chromatography/mass spectrometry (GC/MS) and liquid chromatography/mass spectrometry (LC/MS)