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Toxicological and metabolic considerations for histone deacetylase inhibitors

✍ Scribed by Fraczek, Joanna; Vanhaecke, Tamara; Rogiers, Vera

Book ID
118235626
Publisher
Informa plc
Year
2013
Tongue
English
Weight
690 KB
Volume
9
Category
Article
ISSN
1742-5255

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## Abstract Histone deacetylase (HDAC), inhibitors represent a new class of targeted anti‐cancer agents. Several of these compounds are in clinical trials with significant activity against a spectrum of both hematologic and solid tumors at doses that are well tolerated by the patients. The HDAC inh