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Toxicity of OKT3 increases with dosage: a controlled study in renal transplant recipients

✍ Scribed by Karine J. Parlevliet; Frederike J. Bemelman; Si-La Yong; C. Erik Hack; Janto Surachno; Joep M. Wilmink; Ineke J.M. ten Berge; Peter T.A. Schellekens


Book ID
115134509
Publisher
Springer
Year
1995
Tongue
English
Weight
525 KB
Volume
8
Category
Article
ISSN
0934-0874

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## Abstract Orthoclone OKT3 is a murine monoclonal antibody that blocks the generation and function of T lymphocytes. It has been shown to be effective in reversing acute cellular rejection in solid organ transplants. However, potential development of antimurine antibodies restricts the duration th