𝔖 Bobbio Scriptorium
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Toxicity from methotrexate may be dose related

✍ Scribed by William S. Wilke; Allen H. Mackenzie; Arthur L. Scherbel; Gerald D. Groff; Thomas H. Taylor

Book ID
101646968
Publisher
John Wiley and Sons
Year
1983
Tongue
English
Weight
208 KB
Volume
26
Category
Article
ISSN
0004-3591

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✦ Synopsis

119

joints. There was a modest reduction in the sedimentation rate in the 2 patients with rheumatoid arthritis, but no change in their rheumatoid factor titers.

Despite the unpredictable spontaneous variations in rheumatoid and psoriatic arthritis, the observed clinical improvement in these 3 patients while on phenytoin therapy merits further study.

πŸ“œ SIMILAR VOLUMES

High dose methotrexate therapy of solid
High dose methotrexate therapy of solid tumors: observations relating to clinical toxicity
✍ Isacoff, William H. ;Townsend, Courtney M. ;Eilber, Frederick R. ;Forster, Terry πŸ“‚ Article πŸ“… 1976 πŸ› John Wiley and Sons 🌐 English βš– 464 KB

## Abstract In clinical studies performed during 111 infusions of high dose methotrexate (MTX) we have evolved a clinical and laboratory protocol which permits such therapy without prohibitive risk to the patient. The plasma MTX data obtained indicate that pharmacokinetic disposition is dose relate