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Toxicity from chemoradiotherapy in older patients with glioblastoma multiforme

✍ Scribed by Angelique E. Sijben; John B. McIntyre; Gloria B. Roldán; Jacob C. Easaw; Elizabeth Yan; Peter A. Forsyth; Ian F. Parney; Anthony M. Magliocco; Hans Bernsen; J. Gregory Cairncross

Publisher
Springer US
Year
2008
Tongue
English
Weight
203 KB
Volume
89
Category
Article
ISSN
0167-594X

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## Abstract Alterations in the signal transduction pathways are key mechanisms in the pathogenesis of __de novo__ glioblastoma multiforme (GBM), which are also involved in the resistance to chemo‐ and radiotherapy. Here, we analyzed the methylation status and mRNA expression of suppressor of cytoki