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Impact of novelPTENmutations in Turkish patients with glioblastoma multiforme

✍ Scribed by Berrin Tunca; Ahmet Bekar; Gulsah Cecener; Unal Egeli; Ozgur Vatan; Sahsine Tolunay; Hasan Kocaeli; Kaya Aksoy

Publisher
Springer US
Year
2006
Tongue
English
Weight
263 KB
Volume
82
Category
Article
ISSN
0167-594X

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## Abstract Alterations in the signal transduction pathways are key mechanisms in the pathogenesis of __de novo__ glioblastoma multiforme (GBM), which are also involved in the resistance to chemo‐ and radiotherapy. Here, we analyzed the methylation status and mRNA expression of suppressor of cytoki