Enhanced protein production by engineere
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Andreas Reik; Yuanyue Zhou; Trevor N. Collingwood; Lyndon Warfe; Victor Bartsevi
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Article
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2007
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John Wiley and Sons
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English
โ 335 KB
๐ 2 views
## Abstract Increasing the yield of therapeutic proteins from mammalian production cell lines reduces costs and decreases the time to market. To this end, we engineered a zinc finger protein transcription factor (ZFP TF) that binds a DNA sequence within the promoter driving transgene expression. Th