Towards the understanding of Down syndrome using mouse models
β Scribed by Kazuhiro Yamakawa
- Book ID
- 114825202
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- English
- Weight
- 511 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0914-3505
No coin nor oath required. For personal study only.
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## Abstract Down Syndrome (DS) caused by trisomy 21 is characterized by a variety of phenotypes and involves multiple organs. Sequencing of human chromosome 21 (HSA21) and subsequently of its orthologues on mouse chromosome 16 have created an unprecedented opportunity to explore the complex relatio
One of the most common genetic disorders, Down syndrome has involved physicians and scientists from many disciplines in the attempt t o understand the varied and sometimes specific phenotypes resulting from the presence of extra genetic material on human chromosome 21. Among the nervous system pheno