Mouse models of cognitive disabilities in trisomy 21 (Down syndrome)
✍ Scribed by Pierre L. Roubertoux; Michèle Carlier
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 207 KB
- Volume
- 154C
- Category
- Article
- ISSN
- 1552-4868
No coin nor oath required. For personal study only.
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## Abstract Little is known about the pathogenesis of the phenotype in individuals with trisomy 21 mosaicism and Down syndrome. The primary goal of this study was to identify factors contributing to the observed phenotypic variation by evaluating 107 individuals having trisomy 21 mosaicism. To inve
## Individuals with translocation Down syndrome (DS) often inherit the rearranged chromosome from a carrier parent. DS due to inheritance of one Robertsonian or derivative (14q21q) from one parent and a second der(14q21q) in addition to a free chromosome 21 from the other parent are rarely documen