Towards Biocatalytic Synthesis of β-Lactam Antibiotics
✍ Scribed by Margreth A. Wegman; Michiel H. A. Janssen; Fred van Rantwijk; Roger A. Sheldon
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 438 KB
- Volume
- 343
- Category
- Article
- ISSN
- 1615-4150
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📜 SIMILAR VOLUMES
The stereoselective synthesis of two precursors of tricyclic β-ring-forming reaction followed by the reduction of a functionalized aromatic substituent at C-4 of the β-lactam lactam antibiotics (trinems) has been attempted by a novel approach that involves a highly stereoselective azetidinone nucleu
GV118819X, a novel tricyclic -lactam antibiotic of GlaxoWellcome, is a racemic mixture of two diastereoisomers, A and B. Of the two diastereoisomers, only A is available as a pure compound. By analyzing mixtures of GV118819X and A, a partial phase diagram is constructed, which indicates the presenc