𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Towards and Understanding of Organic Anion Transporters: Structure—Function Relationships.

✍ Scribed by Guofeng You


Publisher
John Wiley and Sons
Year
2004
Weight
7 KB
Volume
35
Category
Article
ISSN
0931-7597

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Towards an understanding of organic anio
✍ Guofeng You 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 179 KB

## Abstract Organic anion transporters (OAT) play essential roles in the body disposition of clinically important anionic drugs, including anti‐viral drugs, anti‐tumor drugs, antibiotics, anti‐hypertensives, and anti‐inflammatories. The activities of OATs are directly linked to drug toxicity and dr

Structure, function, and regulation of r
✍ Guofeng You 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 157 KB

## Abstract Renal elimination of anionic drugs, xenobiotics, and toxins is necessary for the survival of mammalian species. This process is mediated by vectorial transport from blood to urine through the cooperative functions of specific transporters in the basolateral and apical membranes of the p

Identification and functional characteri
✍ G Kullak-Ublick; U Beuers; C Fahney; B Hagenbuch; P J Meier; G Paumgartner 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 298 KB

The organic anion transporting polypeptide (OATP) of the basolateral hepatocyte membrane mediates multispecific uptake of anionic and other amphipathic substrates from sinusoidal blood plasma. To investigate the mechanisms controlling OATP expression, the 5'-flanking region of the human OATP gene wa