𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Structure, Function, and Regulation of Renal Organic Anion Transporters

✍ Scribed by Guofeng You


Publisher
John Wiley and Sons
Year
2003
Weight
71 KB
Volume
34
Category
Article
ISSN
0931-7597

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Structure, function, and regulation of r
✍ Guofeng You 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 157 KB

## Abstract Renal elimination of anionic drugs, xenobiotics, and toxins is necessary for the survival of mammalian species. This process is mediated by vectorial transport from blood to urine through the cooperative functions of specific transporters in the basolateral and apical membranes of the p

Towards an understanding of organic anio
✍ Guofeng You 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 179 KB

## Abstract Organic anion transporters (OAT) play essential roles in the body disposition of clinically important anionic drugs, including anti‐viral drugs, anti‐tumor drugs, antibiotics, anti‐hypertensives, and anti‐inflammatories. The activities of OATs are directly linked to drug toxicity and dr

Interaction of hydroxycinnamic acids and
✍ Chi C. Wong; Denis Barron; Caroline Orfila; Fabiola Dionisi; Peter Krajcsi; Gary 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 357 KB

## Abstract **Scope:** Hydroxycinnamic acids are abundant antioxidants in our diet. In humans, hydroxycinnamic acids are metabolized to form sulfates and glucuronides, with the majority recovered in urine. **Methods and results:** We assessed the potential roles of organic anion transporters (OATs

Renal excretion of emtricitabine I: Effe
✍ Tomoko Nakatani-Freshwater; David R. Taft 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 134 KB

The excretion of emtricitabine (FTC) was characterized using isolated perfused rat kidney (IPK) model. Studies were performed to assess the dose-linearity of FTC excretion, to evaluate the effect of inhibitors of organic anion (probenecid, PBC), organic cation (tetraethylammonium, TEA; cimetidine, C