Towards a truly integrative biology through the functional genomics of yeast
β Scribed by Daniela Delneri; Francesco L Brancia; Stephen G Oliver; Francesco L Brancia
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 57 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0958-1669
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β¦ Synopsis
A complete library of mutant Saccharomyces cerevisiae strains, each deleted for a single representative of yeast's 6000 protein-encoding genes, has been constructed. This represents a major biological resource for the study of eukaryotic functional genomics. However, yeast is also being used as a test-bed for the development of functional genomic technologies at all levels of analysis, including the transcriptome, proteome and metabolome.
π SIMILAR VOLUMES
A principal aim of post-genomic biology is elucidating the structures, functions and biochemical properties of all gene products in a genome. However, to adequately comprehend such a large amount of information we need new descriptions of proteins that scale to the genomic level. In short, we need a