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Towards a general solid phase approach for the iterative synthesis of conjugated oligomers using a germanium based linker - first solid phase synthesis of an oligo-(triarylamine)

✍ Scribed by Turner, David J.; An?mian, R?mi; Mackie, Philip R.; Cupertino, Domenico C.; Yeates, Stephen G.; Turner, Michael L.; Spivey, Alan C.

Book ID
118743732
Publisher
Royal Society of Chemistry
Year
2007
Tongue
English
Weight
388 KB
Volume
5
Category
Article
ISSN
1477-0520

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Three peptide-oligonucleotide phosphorothioate hybrids were synthesized using a new approach for stepwise solidphase synthesis of conjugates. This method utilizes commercially available N a -Fmoc amino acids for peptide synthesis and a new solid support. Three specific modifications of the solid-pha