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Toward Understanding the Role of Angiomotin Lipid Binding in Cellular Proliferation and Migration

✍ Scribed by Kimble-Hill, Ann C.; Jimenez-Segovia, Ilse; Firestone, Millicent A.; Hurley, Thomas D.; Wells, Clark D.


Book ID
122252617
Publisher
Biophysical Society
Year
2013
Tongue
English
Weight
38 KB
Volume
104
Category
Article
ISSN
0006-3495

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## Abstract A congeneric series of four bis‐benzamidine inhibitors sharing a dianhydrosugar isosorbide scaffold in common has been studied by crystal structure analysis and enzyme kinetics with respect to their binding to trypsin and factorβ€…Xa. Within the series, aromatic interactions are an import