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Toward Understanding the Role of Amot80 Lipid Binding in Cellular Proliferation and Migration

✍ Scribed by Donovan, Emily L.; Kimble-Hill, Ann C.; Hurley, Thomas D.; Wells, Clark D.

Book ID
122130825
Publisher
Biophysical Society
Year
2014
Tongue
English
Weight
39 KB
Volume
106
Category
Article
ISSN
0006-3495

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## Abstract A congeneric series of four bis‐benzamidine inhibitors sharing a dianhydrosugar isosorbide scaffold in common has been studied by crystal structure analysis and enzyme kinetics with respect to their binding to trypsin and factorβ€…Xa. Within the series, aromatic interactions are an import