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Toward the semisynthesis of multidomain transmembrane receptors: Modification of Eph tyrosine kinases

โœ Scribed by Nikhil Singla; Juha Pekka Himanen; Tom W. Muir; Dimitar B. Nikolov


Book ID
119824300
Publisher
Cold Spring Harbor Laboratory Press
Year
2008
Tongue
English
Weight
441 KB
Volume
17
Category
Article
ISSN
0961-8368

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โœ Masaru Nakamoto; Andrew D. Bergemann ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 94 KB

The Eph family of receptor tyrosine kinases and their cell-presented ligands, the ephrins, are frequently overexpressed in a wide variety of cancers, including breast, small-cell lung and gastrointestinal cancers, melanomas, and neuroblastomas. In particular, one Eph family member, EphA2, is overexp