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Toward the gene(s) for Wiedemann-Beckwith syndrome and associated tumors in 11p15

✍ Scribed by I. Henry; V. Chéhensse; C. Boulevin; C. Jeanpierre; P. Little; C. Junien


Book ID
119106233
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
129 KB
Volume
77
Category
Article
ISSN
0165-4608

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## Abstract Beckwith–Wiedemann syndrome (BWS) is an overgrowth syndrome characterized by macrosomia, macroglossia, omphalocele, hemihyperplasia, and increased tumor risk. BWS can be associated with genetic and/or epigenetic alterations that modify imprinted gene expression on chromosome 11p15.5. So