Allele-specific methylated multiplex rea
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Salah Azzi; Virginie Steunou; Alexandra Rousseau; Sylvie Rossignol; Nathalie Thi
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Article
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2011
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John Wiley and Sons
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English
⚖ 349 KB
👁 1 views
Many human syndromes involve a loss of imprinting (LOI) due to a loss (LOM) or a gain of DNA methylation (GOM). Most LOI occur as mosaics and can therefore be difficult to detect with conventional methods. The human imprinted 11p15 region is crucial for the control of fetal growth, and LOI at this l