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Toward a total synthesis of brassinosteroids; structure assessment of the Ireland–Claisen products of geranyl and neryl esters

✍ Scribed by O. Temmem; D. Uguen; A. De Cian; N. Gruber

Publisher
Elsevier Science
Year
2002
Tongue
French
Weight
147 KB
Volume
43
Category
Article
ISSN
0040-4039

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✦ Synopsis

As estimated by 1 H NMR analysis, thermal isomerisation of the kinetic silylenolate derived from the ester (Z)-8a proceeds with acceptable diastereo and facial selectivity, thence affording an acid having the required absolute configuration for further elaboration to brassinosteroids.

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