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Toward a quantitative approach for the prediction of the fraction of dose absorbed using the absorption potential concept

✍ Scribed by Panayotis E. Macheras; Mira Y. Symillides

Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
524 KB
Volume
10
Category
Article
ISSN
0142-2782

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✦ Synopsis

An equation based on the absorption potential concept was developed. This enabled us to establish an approach for the quantitative prediction of the fraction of dose absorbed. Classification of drugs into three broad categories, according to their absorption potential values in relation to the fraction of dose absorbed, was attempted. The new approach was tested using literature data with very good results.

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