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Totally synthetic (±)-13-Alkyl-3-hydroxy and methoxy-gona-1,3,5(10)-trien-17-ones and related compounds

✍ Scribed by H. Smith; G. A. Hughes; G. H. Douglas; D. Hartley; B. J. McLoughlin; J. B. Siddall; G. R. Wendt; G. C. Buzby; D. R. Herbst; K. W. Ledig; J. R. McMenamin; T. W. Pattison; J. Suida; J. Tokolics; R. A. Edgren; A. B. A. Jansen; B. Gadsby; D. H. R. Watson; P. C. Phillips


Book ID
112709807
Publisher
Springer
Year
1963
Tongue
English
Weight
393 KB
Volume
19
Category
Article
ISSN
1420-682X

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✍ G. Michael Blackburn; Brian F. Taylor; Andrew F. Worrall 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 French ⚖ 373 KB 👁 1 views

Deuterium NMR spectroscopy has been used to show that a previously published synthesis of t6d,17r-epoxy-3-hydroxy-~~-3H]oestra~~l,3,5(10)-triene is not regiospecific but leads to additional isotope incorporation at positions -2 and/or -4. A modified synthesis i s described which leads to the title c