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Total Synthesis of (−)-Zampanolide and Structure-Activity Relationship Studies on (−)-Dactylolide Derivatives

✍ Scribed by Zurwerra, Didier; Glaus, Florian; Betschart, Leo; Schuster, Julia; Gertsch, Jürg; Ganci, Walter; Altmann, Karl-Heinz


Book ID
118754222
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
503 KB
Volume
18
Category
Article
ISSN
0947-6539

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Diastereoselective construction of cis 2
✍ Teck-Peng Loh; Jian-Ying Yang; Li-Chun Feng; Yan Zhou 📂 Article 📅 2002 🏛 Elsevier Science 🌐 French ⚖ 129 KB

Diastereoselective construction of 2,6-disubstituted tetrahydropyrans with an exocyclic double bond was achieved via the In(OTf) 3 -catalyzed intramolecular 2,5-oxonium-ene cyclization. Its application was further demonstrated by the synthesis of a common intermediate for both zampanolide and dactyl