Total synthesis of thromboxane B2 starting from (R,R)-tartaric acid as a chiral pool
β Scribed by Yukio Masaki; Kazuhiro Yoshizawa; Akichika Itoh
- Book ID
- 108386506
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- French
- Weight
- 206 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0040-4039
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Acetamide-acetal Clai~n rearrangement of the C2-symmetric enediol easily derived from D-mannitol provided a chiral C8-building block, which was demonstrated to be versatile for divergent synthesis of both enantiomeric forms of substituted paraconic acids.