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Total Synthesis of the Squalene Synthase Inhibitor Zaragozic Acid C

✍ Scribed by Seiichi Nakamura

Publisher
John Wiley and Sons
Year
2005
Weight
8 KB
Volume
36
Category
Article
ISSN
0931-7597

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Total Synthesis of the Squalene Synthase
Total Synthesis of the Squalene Synthase Inhibitor Zaragozic Acid C by a Carbonyl Ylide Cycloaddition Strategy
✍ Seiichi Nakamura; Yuuki Hirata; Takahiro Kurosaki; Masahiro Anada; Osamu Kataoka πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 149 KB πŸ‘ 2 views

The zaragozic acids and squalestatins, a novel family of fungal metabolites isolated and characterized by researchers at Merck [1] and Glaxo, [2] respectively, in 1992, are the most potent inhibitors of squalene synthase known to date. [3] Some members of this family have also demonstrated the abili

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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v