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Total Synthesis of the Phytotoxic Agent Herbarumin II Using Butane Diacetals of Glycolic Acid as Building Blocks.

✍ Scribed by Elena Diez; Darren J. Dixon; Steven V. Ley; Alessandra Polara; Felix Rodriguez


Publisher
John Wiley and Sons
Year
2003
Weight
104 KB
Volume
34
Category
Article
ISSN
0931-7597

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The Use of Butane Diacetals of Glycolic
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## Abstract The total synthesis of phytotoxic nonenolide herbarumin II (**1**) has been achieved by implementation of butane diacetal (BDA)‐desymmetrised glycolate building blocks. Three of the four stereogenic centres present in the key coupling fragments were generated from both enantiomeric form

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