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Total Synthesis of the Formamicin Aglycon, Formamicinone.

โœ Scribed by Brad M. Savall; Nicolas Blanchard; William R. Roush


Publisher
John Wiley and Sons
Year
2003
Weight
8 KB
Volume
34
Category
Article
ISSN
0931-7597

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The callipeltosides were isolated by Minale and co-workers from the shallow-water lithistid sponge Callipelta sp., collected off the east coast of New Caledonia. [1a,b] Callipeltoside A (1 in Scheme 1, obtained in 1.4 ร‚ 10 ร€4 % yield) was found to inhibit in vitro the proliferation of KB and P388 ce