Total synthesis of (+)-synargentolide A
β Scribed by J.S. Yadav; B. Thirupathaiah; Vinay K. Singh; V. Ravishashidhar
- Book ID
- 119375865
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 509 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0957-4166
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## Abstract The stereoselective total synthesis of a naturally occurring __Ξ±__βpyrone (=2__H__βpyranβ2βone) derivative, synargentolide A (**1**), and of its epimer **2** (with the originally proposed structure of synargentolide A) was efficiently accomplished involving Dβtartaric acid as the starti
The first stereoselective total synthesis of synargentolide A isolated from Syncolostemon argenteus has been achieved from commercially available (R)-benzyl glycidyl ether using Sharpless asymmetric epoxidation and cross-metathesis reactions as the key steps. Comparing the spectral data of the synth
On pages 6301 and 6302, the spectral and analytical data for compounds 1 and 6 were incorrectly reported.