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Total Synthesis of Rutamycin B, a Macrolide Antibiotic from Streptomyces a ureofaciens

โœ Scribed by White, James D.; Hanselmann, Roger; Jackson, Randy W.; Porter, Warren J.; Ohba, Yoshihiro; Tiller, Thomas; Wang, Shan

Book ID
124087399
Publisher
American Chemical Society
Year
2001
Tongue
English
Weight
228 KB
Volume
66
Category
Article
ISSN
0022-3263

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Synthesis of the macrolide antibiotic A2
Synthesis of the macrolide antibiotic A26771B methyl ester
โœ T.A. Hase; E.-L. Nylund ๐Ÿ“‚ Article ๐Ÿ“… 1979 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 210 KB

The total synthesis of the title compound (1) is reported. The isolation and structure elucidation of the 16-membered lactone antibiotic A2677lB (1) from PeniciZZium turbatum (Westling) was recently reportedl. The compound shows optical activity but its absolute (and relative) stereostructure is u