𝔖 Bobbio Scriptorium
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Total synthesis of pseudoguaianolides. IV: a stereoselective approach to balduilin

✍ Scribed by Lansbury, Peter T.; Mazur, Duane J.; Springer, James P.


Book ID
126849972
Publisher
American Chemical Society
Year
1985
Tongue
English
Weight
757 KB
Volume
50
Category
Article
ISSN
0022-3263

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## Abstract The stereocontrolled synthesis of goniothalesdiol A, a dihydroxylated tetrahydropyran compound, has been accomplished using D‐ribose as chiral precursor. The key steps involved are aryl __Grignard__ reaction, stereoselective alkoxy‐directed keto reduction, and intramolecular oxy‐__Micha