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Total synthesis of PDE-I and -II by copper-mediated double aryl amination

✍ Scribed by Okano, Kentaro; Mitsuhashi, Nakako; Tokuyama, Hidetoshi


Book ID
122126511
Publisher
Elsevier Science
Year
2013
Tongue
French
Weight
836 KB
Volume
69
Category
Article
ISSN
0040-4020

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ChemInform Abstract: Total Synthesis of
✍ Kentaro Okano; Nakako Mitsuhashi; Hidetoshi Tokuyama πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 21 KB

## Abstract Natural product PDE‐II (IV) is prepared via an efficient copper‐catalyzed transformation of tetrahydroisoquinoline (II) into pyrroloindole (III) as key step.