ChemInform Abstract: Total Synthesis of PDE-II by Copper-Mediated Double Amination.

✍ Scribed by Kentaro Okano; Nakako Mitsuhashi; Hidetoshi Tokuyama

• Book ID: 102048152
• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 21 KB
• Volume: 41
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.201035219

✦ Synopsis

Abstract

Natural product PDE‐II (IV) is prepared via an efficient copper‐catalyzed transformation of tetrahydroisoquinoline (II) into pyrroloindole (III) as key step.