Total synthesis of (+--oudemansin
✍ Scribed by Tadashi Nakata; Takaaki Kuwabara; Yōichirō Tani; Takeshi Oishi
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- French
- Weight
- 131 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
f)-Oudemansin has been synthesized starting from N-cinnamaldehyde by a route lnvolvlng the stereoselective Zn(BH4)2 reduction of B-keto ester.
📜 SIMILAR VOLUMES
Oudemansin B (1) synthesized from (ZR,3S)-2,3-epoxybutyrate 2, based on microbial asymmetric r$duction of ketone was proved to be identical with natural oudemansin B (l), which established that the absolute configuration of j\_ is 9S, 10s. Oudemansin B (l\_) is an antibiotics isolated from mycelial
## Abstract Die Darstellung der vier optisch reinen (__E__)‐3‐hydroxy‐2‐methyl‐5‐phenyl‐4‐pentensäure‐methylester (+)‐ und (‐)‐**6** gelingt durch aufeinanderfolgende Methylierung und Protonierung von Esterenolaten, ausgehend von (+)‐ und (‐)‐**4**. Die Ester (+)‐**6** und (‐)‐**5** werden für Synt