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Total synthesis of homalicine and its related dihydro aglycon

✍ Scribed by Khosrow Zamani; Nasim Hassan Rama; Rashid Iqbal

Book ID
102344298
Publisher
Journal of Heterocyclic Chemistry
Year
2000
Tongue
English
Weight
294 KB
Volume
37
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

The condensation of homophthalic acid (1) with 3‐methoxybenzoyl chloride, followed by demethylation gave 3‐(3‐hydroxyphenyl)isocoumarin (3b). Reaction of (3b) with α‐tetraacetobromo glucose yielded tetraacetylhomalicine (3d), which was deacetylated to homalicine (3e).

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