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Total Synthesis of Epothilones B and D: Stannane Equivalents for β-Keto Ester Dianions

✍ Scribed by Keck, Gary E.; Giles, Robert L.; Cee, Victor J.; Wager, Carrie A.; Yu, Tao; Kraft, Matthew B.


Book ID
115314194
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
701 KB
Volume
73
Category
Article
ISSN
0022-3263

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An efficient synthesis of pyrazolo[3,4-b
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## Abstract magnified image 5‐Chloroethylpyrazolo[3,4‐__b__]pyridines were synthesized by condensation of 5‐aminopyrazoles with α‐acetyl γ‐butyrolactone followed by cyclization treating with phosphorous oxychloride. 5‐Chloroethyl‐pyrazolo[3,4‐__b__]pyridines, thus obtained, were then converted to