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Total Synthesis of Diplamine, a Cytotoxic Pyridoacridine Alkaloid from a Pacific Tunicate

โœ Scribed by Szczepankiewicz, Bruce G.; Heathcock, Clayton H.

Book ID
126311498
Publisher
American Chemical Society
Year
1994
Tongue
English
Weight
232 KB
Volume
59
Category
Article
ISSN
0022-3263

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๐Ÿ“œ SIMILAR VOLUMES

Total synthesis of the marine pyridoacri
Total synthesis of the marine pyridoacridine alkaloid sebastianine A
โœ Laurent Legentil; Jean Bastide; Evelyne Delfourne ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 81 KB

The synthesis of the marine alkaloid sebastianine A and of a regioisomer has been accomplished via hetero-Diels-Alder reaction of indole-4,7-dione or N-tosylindole-4,7-dione with trifluoroacetamidocinnamaldehyde dimethylhydrazone, and subsequent cyclisation in alkaline conditions.