Total Synthesis of (-)-Dihydrocorynantheol (IV) Using Bicyclo[3.2.1]octenone Chiral Building Block (I).
โ Scribed by Ayako Tosaka; Shinichiro Ito; Norio Miyazawa; Masatoshi Shibuya; Kunio Ogasawara; Yoshiharu Iwabuchi
- Publisher
- John Wiley and Sons
- Year
- 2007
- Weight
- 19 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0931-7597
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โฆ Synopsis
Abstract
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๐ SIMILAR VOLUMES
An efficient synthesis of optically active (2R,3R)-2-methyl-3-[(1R)-1-methylprop-2-enyl]cyclopentanone, a useful chiral building block for synthesis of vitamin D and steroids, has been developed starting from readily accessible optically active secondary propargyl phosphate (R)-2, where the asymmetr