𝔖 Bobbio Scriptorium
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Total Synthesis of (-)-Dictyostatin.

✍ Scribed by Gregory W. O'Neil; Andrew J. Phillips

Publisher
John Wiley and Sons
Year
2006
Weight
11 KB
Volume
37
Category
Article
ISSN
0931-7597

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πŸ“œ SIMILAR VOLUMES

A Highly Stereoselective Total Synthesis
A Highly Stereoselective Total Synthesis of (+)-9-epi-Dictyostatin
✍ Chiara Zanato; Luca Pignataro; Andrea Ambrosi; Zhongyan Hao; Cesare Gennari πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 192 KB

## Abstract The total synthesis of (+)‐9‐__epi__‐dictyostatin (**1b**), a diastereomer of the antimitotic marine‐sponge‐derived macrolide (–)‐dictyostatin (**1a**), was achieved by creating 11 stereogenic centers and 4 stereogenic double bonds with a high level of stereocontrol. The yield for the 2