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Total Synthesis of (+)-Dactylolide through an Efficient Sequential Peterson Olefination and Prins Cyclization Reaction

✍ Scribed by Danielle L. Aubele; Shuangyi Wan; Paul E. Floreancig


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
315 KB
Volume
44
Category
Article
ISSN
0044-8249

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Total Synthesis of (+)-3-Oxacarbacyclin. Part 1. Retrosynthesis and Asymmetric Olefination Through Horner-Wadsworth-Emmons, Peterson and Martin Reactions. -The Horner-Wadsworth-Emmons reaction of the ketones (I) and (V) with the phosphonates (II), (VI), and (IXb), the Peterson reaction of (V) with