Total synthesis of (+)-crocacin C
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Tushar K Chakraborty; Sarva Jayaprakash
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Article
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2001
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Elsevier Science
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French
⚖ 85 KB
The first synthesis of ( +)-crocacin C (3) in optically pure form is achieved following a convergent strategy. The synthesis also establishes the absolute stereochemistries of this novel class of potent antifungal and highly cytotoxic compounds. The naturally occurring crocacin C has (6S,7S,8R,9S) c