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Total Synthesis of (–)-Corynantheidine by Nickel-Catalyzed Carboxylative Cyclization of Enynes

✍ Scribed by Takashi Mizuno; Yoshihiro Oonishi; Masanori Takimoto; Yoshihiro Sato


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
181 KB
Volume
2011
Category
Article
ISSN
1434-193X

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Riccardin B, a macrocyclic bis(bibenzy1) possessing cytotoxic activity, and its dehydroxy derivative were synthesized in high yields using the nickel-catalyzed intramolecular coupling of the acyclic precursors.